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Targets Recommended: Bombesin Receptor

3

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T10722 CD80-IN-3

Bombesin Receptor GPCR/G Protein
CD80-IN-3 是一种CD80抑制剂,抑制 CD80/CD28 互作的EC50=630 nM,Kd=125 nM。
T64239 Belatacept

Belatacept (BMS 224818) 是一种选择性的 T 细胞共刺激 (T-cell costimulation) 阻滞剂。Belatacept 能够结合 CD 80/86 配体,从而对 CD-28 介导的 T 细胞共刺激表现出抑制作用。Belatacept 能够用于研究器官移植免疫抑制。
T38100 Betamethasone 21-phosphate (sodium salt hydrate)

Betamethasone 21-phosphate is a synthetic glucocorticoid.1It prevents increases in macrophage and eosinophil numbers in bronchoalveolar lavage fluid (BALF) and decreases in blood leukocyte numbers in a guinea pig model of parainfluenza-3 viral infection when administered at a dose of 8 mg/kg but does not prevent airway hyperresponsiveness after infection.2Betamethasone 21-phosphate inhibits cell infiltration into the aqueous humor in a rat model of endotoxin-induced uveitis when administered top...

化合物

CD80-IN-3
Cat.No: T10722
Synonym:
Target: Bombesin Receptor
Belatacept
Cat.No: T64239
Synonym:
Target:
Betamethasone 21-phosphate (sodium salt hydrate)
Cat.No: T38100
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00958 B7-1 Protein, Rabbit, Recombinant (His)

Activation B7-1 antigen,T-lymphocyte activation antigen ...

Rabbit HEK293 Cells
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ...
TMPJ-00630 B7-1 Protein, Cynomolgus, Recombinant (hFc)

B7,CD80,T-lymphocyte activation antigen

Cynomolgus HEK293 Cells
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the ...
TMPK-00179 B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated

B7.1,CD80,B7,CD80 molecu...

Human HEK293 Cells
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.8 kDa and the accession number is P33681-1.
TMPK-00178 B7-1 Protein, Human, Recombinant (His & Avi)

B71,CD80,BB1,LAB7,B7-1,B7.1,B7,CD...

Human HEK293 Cells
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. B7-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.8 kDa and the accession number is P33681-1.
TMPJ-00291 IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated

IL-6R-α,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Int...

Human HEK293 Cells
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an...

重组蛋白

B7-1 Protein, Rabbit, Recombinant (His)
Cat.No: TMPJ-00958
Species: Rabbit
Expression System: HEK293 Cells
B7-1 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-00630
Species: Cynomolgus
Expression System: HEK293 Cells
B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated
Cat.No: TMPK-00179
Species: Human
Expression System: HEK293 Cells
B7-1 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00178
Species: Human
Expression System: HEK293 Cells
IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00291
Species: Human
Expression System: HEK293 Cells
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